Mismatch repair protein hMSH2–hMSH6 recognizes mismatches and forms sliding clamps within a D-loop recombination intermediate

High fidelity homologous DNA recombination depends on mismatch repair (MMR), which antagonizes recombination between divergent sequences by rejecting heteroduplex DNA containing excessive nucleotide mismatches. The hMSH2–hMSH6 heterodimer is the first responder in postreplicative MMR and also plays...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Honda, Masayoshi, Okuno, Yusuke, Hengel, Sarah R., Martín-López, Juana V., Cook, Christopher P., Amunugama, Ravindra, Soukup, Randal J., Subramanyam, Shyamal, Fishel, Richard, Spies, Maria
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903253/
https://ncbi.nlm.nih.gov/pubmed/24395779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312988111
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