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Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair

The MutS (MSH) and MutL (MLH) homologs are conserved proteins that function in mismatch repair (MMR) and meiosis. We examined mRNA and protein expression of hMLH3 compared to other human MSH and MLH in a panel of human tissues and the HeLa cell line. Quantitative PCR suggests that MSH and MLH transc...

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Библиографические подробности
Главные авторы: Charbonneau, Nicole, Amunugama, Ravindra, Schmutte, Christoph, Yoder, Kristine, Fishel, Richard
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010362/
https://ncbi.nlm.nih.gov/pubmed/19483466
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