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Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair

The MutS (MSH) and MutL (MLH) homologs are conserved proteins that function in mismatch repair (MMR) and meiosis. We examined mRNA and protein expression of hMLH3 compared to other human MSH and MLH in a panel of human tissues and the HeLa cell line. Quantitative PCR suggests that MSH and MLH transc...

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Détails bibliographiques
Auteurs principaux: Charbonneau, Nicole, Amunugama, Ravindra, Schmutte, Christoph, Yoder, Kristine, Fishel, Richard
Format: Artigo
Langue:Inglês
Publié: 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010362/
https://ncbi.nlm.nih.gov/pubmed/19483466
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