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Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair

The MutS (MSH) and MutL (MLH) homologs are conserved proteins that function in mismatch repair (MMR) and meiosis. We examined mRNA and protein expression of hMLH3 compared to other human MSH and MLH in a panel of human tissues and the HeLa cell line. Quantitative PCR suggests that MSH and MLH transc...

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Detalhes bibliográficos
Main Authors: Charbonneau, Nicole, Amunugama, Ravindra, Schmutte, Christoph, Yoder, Kristine, Fishel, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010362/
https://ncbi.nlm.nih.gov/pubmed/19483466
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