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Control of spontaneous ovarian tumors by CD8+ T cells through NKG2D-targeted delivery of antigenic peptide

BACKGROUND: There is an urgent need to develop targeted therapies for the control of advanced stage ovarian cancer because it is the most deadly gynecologic cancer. Antigen-specific immunotherapy is a promising approach because of the potential of the immune system to specifically target tumors with...

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Autores principales: Kang, Tae Heung, Knoff, Jayne, Yang, Benjamin, Tsai, Ya-Chea, He, Liangmei, Hung, Chien-Fu, Wu, T-C
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903078/
https://ncbi.nlm.nih.gov/pubmed/24354786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-3-48
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