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Buccal injection of synthetic HPV long peptide vaccine induces local and systemic antigen-specific CD8+ T-cell immune responses and antitumor effects without adjuvant

BACKGROUND: Human Papillomavirus is responsible for over 99 % of cervical cancers and is associated with cancers of the head and neck. The currently available prophylactic vaccines against HPV do not generate therapeutic effects against established HPV infections and associated lesions and disease....

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Publicat a:Cell Biosci
Autors principals: Yang, Ming-Chieh, Yang, Andrew, Qiu, Jin, Yang, Benjamin, He, Liangmei, Tsai, Ya-Chea, Jeang, Jessica, Wu, T.-C., Hung, Chien-Fu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778350/
https://ncbi.nlm.nih.gov/pubmed/26949512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-016-0083-9
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