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DNA Vaccines Encoding Ii-PADRE Generates Potent PADRE-specific CD4(+) T-Cell Immune Responses and Enhances Vaccine Potency
It is now clear that CD4(+) T cells play a crucial role in the generation of CD8(+) T effector and memory T-cell immune responses. In this study, we enhanced the CD4(+) T-cell immune responses in mice by constructing a DNA vaccine encoding an invariant (Ii) chain in which the class II–associated Ii...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171992/ https://ncbi.nlm.nih.gov/pubmed/17356542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mt.6300121 |
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