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DNA Vaccines Encoding Ii-PADRE Generates Potent PADRE-specific CD4(+) T-Cell Immune Responses and Enhances Vaccine Potency

It is now clear that CD4(+) T cells play a crucial role in the generation of CD8(+) T effector and memory T-cell immune responses. In this study, we enhanced the CD4(+) T-cell immune responses in mice by constructing a DNA vaccine encoding an invariant (Ii) chain in which the class II–associated Ii...

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Hlavní autoři: Hung, Chien-Fu, Tsai, Ya-Chea, He, Liangmei, Wu, T-C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171992/
https://ncbi.nlm.nih.gov/pubmed/17356542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mt.6300121
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