In vivo microRNA-155 expression influences antigen-specific T cell-mediated immune responses generated by DNA vaccination

BACKGROUND: MicroRNA (miRNA) molecules are potent mediators of post-transcriptional gene silencing that are emerging to be critical in the regulation of innate and adaptive immunity. RESULTS: Here we report that miR-155--an oncogenic miRNA with important function in the mammalian immune system--is i...

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Main Authors: Mao, Chih-Ping, He, Liangmei, Tsai, Ya-Chea, Peng, Shiwen, Kang, Tae Heung, Pang, Xiaowu, Monie, Archana, Hung, Chien-Fu, Wu, T-C
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116247/
https://ncbi.nlm.nih.gov/pubmed/21711593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-1-3
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