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Programmed self-assembly of peptide–major histocompatibility complex for antigen-specific immune modulation

A technology to prime desired populations of T cells in the body—particularly those that possess low avidity against target antigen—would pave the way for the design of new types of vaccination for intractable infectious diseases or cancer. Here, we report such a technology based on positive feedbac...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Mao, Chih-Ping, Peng, Shiwen, Yang, Andrew, He, Liangmei, Tsai, Ya-Chea, Hung, Chien-Fu, Wu, T.-C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924900/
https://ncbi.nlm.nih.gov/pubmed/29632186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718434115
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