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Programmed self-assembly of peptide–major histocompatibility complex for antigen-specific immune modulation

A technology to prime desired populations of T cells in the body—particularly those that possess low avidity against target antigen—would pave the way for the design of new types of vaccination for intractable infectious diseases or cancer. Here, we report such a technology based on positive feedbac...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Mao, Chih-Ping, Peng, Shiwen, Yang, Andrew, He, Liangmei, Tsai, Ya-Chea, Hung, Chien-Fu, Wu, T.-C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924900/
https://ncbi.nlm.nih.gov/pubmed/29632186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718434115
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