Creation of a Merkel cell polyomavirus small T antigen-expressing murine tumor model and a DNA vaccine targeting small T antigen

BACKGROUND: Merkel cell polyomavirus (MCPyV) is a DNA virus expressing transcripts similar to the large T (LT) and small T (ST) transcripts of SV40, which has been implicated in the pathogenesis of Merkel cell carcinoma (MCC), a rare and highly aggressive neuroendocrine skin cancer. MCPyV LT antigen...

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Detalhes bibliográficos
Main Authors: Gomez, Bianca, He, Liangmei, Tsai, Ya Chea, Wu, T-C, Viscidi, Raphael P, Hung, Chien-Fu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750327/
https://ncbi.nlm.nih.gov/pubmed/23856459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-3-29
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