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Targeted Coating With Antigenic Peptide Renders Tumor Cells Susceptible to CD8(+) T Cell-mediated Killing
The potency of immunotherapies targeting endogenous tumor antigens is hindered by immune tolerance. We created a therapeutic agent comprised of a tumor-homing module fused to a functional domain capable of selectively rendering tumor cells sensitive to foreign antigen-specific CD8(+) T cell-mediated...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589158/ https://ncbi.nlm.nih.gov/pubmed/23183537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.233 |
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