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Using passenger mutations to estimate the timing of driver mutations and identify mutator alterations
BACKGROUND: Recent developments in high-throughput genomic technologies make it possible to have a comprehensive view of genomic alterations in tumors on a whole genome scale. Only a small number of somatic alterations detected in tumor genomes are driver alterations which drive tumorigenesis. Most...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3903072/ https://ncbi.nlm.nih.gov/pubmed/24330428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-363 |
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