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Identifying cancer driver genes in tumor genome sequencing studies

Motivation: Major tumor sequencing projects have been conducted in the past few years to identify genes that contain ‘driver’ somatic mutations in tumor samples. These genes have been defined as those for which the non-silent mutation rate is significantly greater than a background mutation rate est...

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Detalhes bibliográficos
Main Authors: Youn, Ahrim, Simon, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018819/
https://ncbi.nlm.nih.gov/pubmed/21169372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq630
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