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Identifying cancer driver genes in tumor genome sequencing studies

Motivation: Major tumor sequencing projects have been conducted in the past few years to identify genes that contain ‘driver’ somatic mutations in tumor samples. These genes have been defined as those for which the non-silent mutation rate is significantly greater than a background mutation rate est...

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Bibliografiske detaljer
Main Authors: Youn, Ahrim, Simon, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018819/
https://ncbi.nlm.nih.gov/pubmed/21169372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq630
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