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Identifying cancer driver genes in tumor genome sequencing studies

Motivation: Major tumor sequencing projects have been conducted in the past few years to identify genes that contain ‘driver’ somatic mutations in tumor samples. These genes have been defined as those for which the non-silent mutation rate is significantly greater than a background mutation rate est...

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Hlavní autoři: Youn, Ahrim, Simon, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018819/
https://ncbi.nlm.nih.gov/pubmed/21169372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq630
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