Llwytho...

Estimating the order of mutations during tumorigenesis from tumor genome sequencing data

Motivation: Tumors are thought to develop and evolve through a sequence of genetic and epigenetic somatic alterations to progenitor cells. Early stages of human tumorigenesis are hidden from view. Here, we develop a method for inferring some aspects of the order of mutational events during tumorigen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Youn, Ahrim, Simon, Richard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465102/
https://ncbi.nlm.nih.gov/pubmed/22492649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts168
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