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Estimating the order of mutations during tumorigenesis from tumor genome sequencing data
Motivation: Tumors are thought to develop and evolve through a sequence of genetic and epigenetic somatic alterations to progenitor cells. Early stages of human tumorigenesis are hidden from view. Here, we develop a method for inferring some aspects of the order of mutational events during tumorigen...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465102/ https://ncbi.nlm.nih.gov/pubmed/22492649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts168 |
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