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Distinguishing between driver and passenger mutations in individual cancer genomes by network enrichment analysis

BACKGROUND: In somatic cancer genomes, delineating genuine driver mutations against a background of multiple passenger events is a challenging task. The difficulty of determining function from sequence data and the low frequency of mutations are increasingly hindering the search for novel, less comm...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Merid, Simon Kebede, Goranskaya, Daria, Alexeyenko, Andrey
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262241/
https://ncbi.nlm.nih.gov/pubmed/25236784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-308
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