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Distinguishing Driver and Passenger Mutations in an Evolutionary History Categorized by Interference

In many biological scenarios, from the development of drug resistance in pathogens to the progression of healthy cells toward cancer, quantifying the selection acting on observed mutations is a central question. One difficulty in answering this question is the complexity of the background upon which...

詳細記述

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書誌詳細
主要な著者: Illingworth, Christopher J. R., Mustonen, Ville
フォーマット: Artigo
言語:Inglês
出版事項: Genetics Society of America 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213378/
https://ncbi.nlm.nih.gov/pubmed/21900272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.133975
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