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Distinguishing Driver and Passenger Mutations in an Evolutionary History Categorized by Interference

In many biological scenarios, from the development of drug resistance in pathogens to the progression of healthy cells toward cancer, quantifying the selection acting on observed mutations is a central question. One difficulty in answering this question is the complexity of the background upon which...

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Bibliografiska uppgifter
Huvudupphovsmän: Illingworth, Christopher J. R., Mustonen, Ville
Materialtyp: Artigo
Språk:Inglês
Publicerad: Genetics Society of America 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213378/
https://ncbi.nlm.nih.gov/pubmed/21900272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.133975
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