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Leveraging protein quaternary structure to identify oncogenic driver mutations

BACKGROUND: Identifying key “driver” mutations which are responsible for tumorigenesis is critical in the development of new oncology drugs. Due to multiple pharmacological successes in treating cancers that are caused by such driver mutations, a large body of methods have been developed to differen...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Ryslik, Gregory A., Cheng, Yuwei, Modis, Yorgo, Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802602/
https://ncbi.nlm.nih.gov/pubmed/27001666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0963-3
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