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Leveraging protein quaternary structure to identify oncogenic driver mutations

BACKGROUND: Identifying key “driver” mutations which are responsible for tumorigenesis is critical in the development of new oncology drugs. Due to multiple pharmacological successes in treating cancers that are caused by such driver mutations, a large body of methods have been developed to differen...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Ryslik, Gregory A., Cheng, Yuwei, Modis, Yorgo, Zhao, Hongyu
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802602/
https://ncbi.nlm.nih.gov/pubmed/27001666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0963-3
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