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New Insights into Molecular Recognition of 1,1-Bisphosphonic Acids by Farnesyl Diphosphate Synthase

As part of our project pointed at the search of new antiparasitic agents against American trypanosomiasis (Chagas disease) and toxoplasmosis a series of 2-alkylaminoethyl-1-hydroxy-1,1-bishosphonic acids has been designed, synthesized and biologically evaluated against the etiologic agents of these...

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Autores principales: Ferrer-Casal, Mariana, Li, Catherine, Galizzi, Melina, Stortz, Carlos A., Szajnman, Sergio H., Docampo, Roberto, Moreno, Silvia N. J., Rodriguez, Juan B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902031/
https://ncbi.nlm.nih.gov/pubmed/24300918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.11.010
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