5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-Monophosphate (AICAR), a Highly Conserved Purine Intermediate with Multiple Effects

AICAR (5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate) is a natural metabolic intermediate of purine biosynthesis that is present in all organisms. In yeast, AICAR plays important regulatory roles under physiological conditions, notably through its direct interactions wi...

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Bibliographic Details
Main Authors: Daignan-Fornier, Bertrand, Pinson, Benoît
Format: Artigo
Language:Inglês
Published: MDPI 2012
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901205/
https://ncbi.nlm.nih.gov/pubmed/24957512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo2020292
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