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Lysophosphatidic acid induces vasodilation mediated by LPA(1) receptors, phospholipase C, and endothelial nitric oxide synthase
Lysophosphatidic acid (LPA) has been implicated as a mediator of several cardiovascular functions, but its potential involvement in the control of vascular tone is obscure. Here, we show that both LPA (18:1) and VPC31143 (a synthetic agonist of LPA(1–3) receptors) relax intact mouse thoracic aorta w...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Federation of American Societies for Experimental Biology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898652/ https://ncbi.nlm.nih.gov/pubmed/24249637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-234997 |
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