Sphingosine-1-Phosphate Enhances α(1)-Adrenergic Vasoconstriction via S1P2–G(12/13)–ROCK Mediated Signaling

Sphingosine-1-phosphate (S1P) has been implicated recently in the physiology and pathology of the cardiovascular system including regulation of vascular tone. Pilot experiments showed that the vasoconstrictor effect of S1P was enhanced markedly in the presence of phenylephrine (PE). Based on this ob...

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Publicat a:Int J Mol Sci
Autors principals: Panta, Cecília R., Ruisanchez, Éva, Móré, Dorottya, Dancs, Péter T., Balogh, Andrea, Fülöp, Ágnes, Kerék, Margit, Proia, Richard L., Offermanns, Stefan, Tigyi, Gábor J., Benyó, Zoltán
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941080/
https://ncbi.nlm.nih.gov/pubmed/31861195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246361
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