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Sphingosine-1-Phosphate Enhances α(1)-Adrenergic Vasoconstriction via S1P2–G(12/13)–ROCK Mediated Signaling

Sphingosine-1-phosphate (S1P) has been implicated recently in the physiology and pathology of the cardiovascular system including regulation of vascular tone. Pilot experiments showed that the vasoconstrictor effect of S1P was enhanced markedly in the presence of phenylephrine (PE). Based on this ob...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Panta, Cecília R., Ruisanchez, Éva, Móré, Dorottya, Dancs, Péter T., Balogh, Andrea, Fülöp, Ágnes, Kerék, Margit, Proia, Richard L., Offermanns, Stefan, Tigyi, Gábor J., Benyó, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941080/
https://ncbi.nlm.nih.gov/pubmed/31861195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246361
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