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Vessel-specific role of sphingosine kinase 1 in the vasoconstriction of isolated basilar arteries
Sphingosine-1-phosphate (S1P) constricts cerebral arteries through S1P(3) receptor stimulation. Because the activity of the key S1P-synthesizing enzyme, sphingosine kinase (SPK), can be stimulated by agonists of various G protein-coupled receptors, it is likely that S1P also acts as a second messeng...
Gorde:
Egile Nagusiak: | , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
2010
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974794/ https://ncbi.nlm.nih.gov/pubmed/20850539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2010.09.002 |
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