Analysis of sphingosine 1-phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools

BACKGROUND AND PURPOSE: Sphingosine 1-phosphate (S1P) selectively and potently constricts isolated cerebral arteries, but this response has not been pharmacologically characterized. EXPERIMENTAL APPROACH: The receptor subtype(s) involved in S1P-induced cerebrovascular constriction were characterized...

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Detalhes bibliográficos
Main Authors: Salomone, S, Potts, E M, Tyndall, S, Ip, P C, Chun, J, Brinkmann, V, Waeber, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199385/
https://ncbi.nlm.nih.gov/pubmed/18026125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707581
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