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Sphingosine-1-phosphate and sphingosylphosphorylcholine constrict renal and mesenteric microvessels in vitro

1. Sphingolipids such as sphingosine-1-phosphate (SPP) and sphingosylphosphorylcholine (SPPC) can act both intracellularly and at G-protein-coupled receptors, some of which were cloned and designated as Edg-receptors. 2. Sphingolipid-induced vascular effects were determined in isolated rat mesenteri...

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Detalhes bibliográficos
Principais autores: Bischoff, Angela, Czyborra, Peter, Fetscher, Charlotte, Meyer zu Heringdorf, Dagmar, Jakobs, Karl H, Michel, Martin C
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572273/
https://ncbi.nlm.nih.gov/pubmed/10952677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703515
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