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Sphingosylphosphorylcholine, a naturally occurring lipid mediator, inhibits human platelet function

1. The lysophospholipids, lysophosphatidic acid and sphingosine 1-phosphate, have been reported to activate platelets. Here we examined effects of the naturally occurring related sphingosylphosphorylcholine (SPC) on human platelet function. 2. Platelet activation was determined as aggregation, eleva...

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Detalhes bibliográficos
Main Authors: Altmann, Christoph, Meyer zu Heringdorf, Dagmar, Böyükbas, Dilek, Haude, Michael, Jakobs, Karl H, Michel, Martin C
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573687/
https://ncbi.nlm.nih.gov/pubmed/12569068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705063
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