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Renal mesangial cells: moving on sphingosine kinase-1
Sphingosine kinase-1 (SphK1) catalyses the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P), which acts on at least five specific G-protein-coupled receptors and also intracellularly. SphK1 has been implicated in cell proliferation, cancer growth, chemoresistance, immune cell function...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2013902/ https://ncbi.nlm.nih.gov/pubmed/17200675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706986 |
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