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Renal mesangial cells: moving on sphingosine kinase-1

Sphingosine kinase-1 (SphK1) catalyses the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P), which acts on at least five specific G-protein-coupled receptors and also intracellularly. SphK1 has been implicated in cell proliferation, cancer growth, chemoresistance, immune cell function...

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Bibliografiska uppgifter
Huvudupphovsmän: Meyer zu Heringdorf, D, Jakobs, K H
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013902/
https://ncbi.nlm.nih.gov/pubmed/17200675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706986
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