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Renal mesangial cells: moving on sphingosine kinase-1

Sphingosine kinase-1 (SphK1) catalyses the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P), which acts on at least five specific G-protein-coupled receptors and also intracellularly. SphK1 has been implicated in cell proliferation, cancer growth, chemoresistance, immune cell function...

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書目詳細資料
Main Authors: Meyer zu Heringdorf, D, Jakobs, K H
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013902/
https://ncbi.nlm.nih.gov/pubmed/17200675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706986
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