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Inhibition of LRRK2 kinase activity stimulates macroautophagy()
Leucine Rich Repeat Kinase 2 (LRRK2) is one of the most important genetic contributors to Parkinson's disease. LRRK2 has been implicated in a number of cellular processes, including macroautophagy. To test whether LRRK2 has a role in regulating autophagy, a specific inhibitor of the kinase acti...
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| Huvudupphovsmän: | , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Elsevier Pub. Co
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898616/ https://ncbi.nlm.nih.gov/pubmed/23916833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.07.020 |
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