Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson’s disease brains with Lewy body pathology

LRRK2, the gene encoding the multidomain kinase Leucine-Rich Repeat Kinase 2 (LRRK2), has been linked to familial and sporadic forms of Parkinson’s disease (PD), as well as cancer, leprosy and Crohn’s disease, establishing it as a target for discovery therapeutics. LRRK2 has been associated with a r...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Mamais, Adamantios, Manzoni, Claudia, Nazish, Iqra, Arber, Charles, Sonustun, Berkiye, Wray, Selina, Warner, Thomas T., Cookson, Mark R., Lewis, Patrick A., Bandopadhyay, Rina
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier/North-Holland Biomedical Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361106/
https://ncbi.nlm.nih.gov/pubmed/30055128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2018.07.023
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