A carregar...

Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function

Pharmacological focal adhesion kinase (FAK) inhibition prevents tumor growth and metastasis, via actions on both tumor and stromal cells. In this paper, we show that vascular endothelial cadherin (VEC) tyrosine (Y) 658 is a target of FAK in tumor-associated endothelial cells (ECs). Conditional kinas...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jean, Christine, Chen, Xiao Lei, Nam, Ju-Ock, Tancioni, Isabelle, Uryu, Sean, Lawson, Christine, Ward, Kristy K., Walsh, Colin T., Miller, Nichol L.G., Ghassemian, Majid, Turowski, Patric, Dejana, Elisabetta, Weis, Sara, Cheresh, David A., Schlaepfer, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897185/
https://ncbi.nlm.nih.gov/pubmed/24446483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201307067
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!