Effect of a tail piece cysteine deletion on biochemical and functional properties of an epidermal growth factor receptor-directed IgA2 m(1) antibody

Antibodies of human IgA isotype are critical components of the mucosal immune system, but little is known about their immunotherapeutic potential. Compared with IgG antibodies, IgA molecules carry a C-terminal tail piece extension of 18 amino acids with a free cysteine at position 471. This cysteine...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Brunke, Christina, Lohse, Stefan, Derer, Stefanie, Peipp, Matthias, Boross, Peter, Kellner, Christian, Beyer, Thomas, Dechant, Michael, Royle, Louise, Liew, Li Phing, Leusen, Jeanette HW, Valerius, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2013
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896607/
https://ncbi.nlm.nih.gov/pubmed/24492345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.26396
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