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Regulation of complement and modulation of its activity in monoclonal antibody therapy of cancer
The complement system is a powerful tool of the innate immune system to eradicate pathogens. Both in vitro and in vivo evidence indicates that therapeutic anti-tumor monoclonal antibodies (mAbs) can activate the complement system by the classical pathway. However, the contribution of complement to t...
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| Publicat a: | MAbs |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622586/ https://ncbi.nlm.nih.gov/pubmed/25517299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.29670 |
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