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Mechanisms of action of CD20 antibodies

Therapeutic monoclonal antibodies (mAbs) that target the CD20 antigen on B cells are successfully used in the clinic for the depletion of B cells to treat various forms of cancer and autoimmune diseases. The first CD20 mAb, approved by the FDA in 1998, was rituximab (RTX) and since then it has been...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Boross, Peter, Leusen, Jeanette H W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: e-Century Publishing Corporation 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512181/
https://ncbi.nlm.nih.gov/pubmed/23226614
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