The in vivo mechanism of action of CD20 monoclonal antibodies depends on local tumor burden

BACKGROUND: CD20 monoclonal antibodies are widely used in clinical practice. Antibody-dependent cellular cytotoxicity, complement-dependent cytotoxicity and direct cell death have been suggested to be important effector functions for CD20 antibodies. However, their specific contributions to the in v...

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Autors principals: Boross, Peter, Jansen, J.H. Marco, de Haij, Simone, Beurskens, Frank J., van der Poel, Cees E., Bevaart, Lisette, Nederend, Maaike, Golay, Josée, van de Winkel, Jan G.J., Parren, Paul W.H.I., Leusen, Jeanette H.W.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2011
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232265/
https://ncbi.nlm.nih.gov/pubmed/21880632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.047159
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