IgA EGFR antibodies mediate tumour killing in vivo

Currently all approved anti-cancer therapeutic monoclonal antibodies (mAbs) are of the IgG isotype, which rely on Fcgamma receptors (FcγRs) to recruit cellular effector functions. In vitro studies showed that targeting of FcαRI (CD89) by bispecific antibodies (bsAbs) or recombinant IgA resulted in m...

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Xehetasun bibliografikoak
Egile Nagusiak: Boross, Peter, Lohse, Stefan, Nederend, Maaike, Jansen, Johannes Hendrik Marco, van Tetering, Geert, Dechant, Michael, Peipp, Matthias, Royle, Louise, Liew, Li Phing, Boon, Louis, van Rooijen, Nico, Bleeker, Wim K, Parren, Paul W H I, van de Winkel, Jan G J, Valerius, Thomas, Leusen, Jeanette H W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2013
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944462/
https://ncbi.nlm.nih.gov/pubmed/23918228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201929
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