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High throughput detection of antibody self-interaction by bio-layer interferometry
Self-interaction of an antibody may lead to aggregation, low solubility or high viscosity. Rapid identification of highly developable leads remains challenging, even though progress has been made with the introduction of techniques such as self-interaction chromatography (SIC) and cross-interaction...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896597/ https://ncbi.nlm.nih.gov/pubmed/23995620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.26186 |
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