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High throughput solution-based measurement of antibody-antigen affinity and epitope binning

Advances in human antibody discovery have allowed for the selection of hundreds of high affinity antibodies against many therapeutically relevant targets. This has necessitated the development of reproducible, high throughput analytical techniques to characterize the output from these selections. Am...

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Hlavní autoři: Estep, Patricia, Reid, Felicia, Nauman, Claire, Liu, Yuqi, Sun, Tingwan, Sun, Joanne, Xu, Yingda
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893237/
https://ncbi.nlm.nih.gov/pubmed/23575269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.23049
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