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Formulated Minimal-Length Synthetic Small Hairpin RNAs Are Potent Inhibitors of Hepatitis C Virus in Mice With Humanized Livers
Short synthetic small-hairpin RNAS (sshRNAs) (SG220 and SG273) that target the internal ribosome entry site of the hepatitis C virus (HCV) were formulated into lipid nano-particles and administered intravenously to HCV-infected urokinase plasminogen activator–severe combined immunodeficient mice wit...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896324/ https://ncbi.nlm.nih.gov/pubmed/24076507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.09.049 |
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