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Structural insights into gene repression by the orphan nuclear receptor SHP
Small heterodimer partner (SHP) is an orphan nuclear receptor that functions as a transcriptional repressor to regulate bile acid and cholesterol homeostasis. Although the precise mechanism whereby SHP represses transcription is not known, E1A-like inhibitor of differentiation (EID1) was isolated as...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896210/ https://ncbi.nlm.nih.gov/pubmed/24379397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322827111 |
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