Structural insights into gene repression by the orphan nuclear receptor SHP

Small heterodimer partner (SHP) is an orphan nuclear receptor that functions as a transcriptional repressor to regulate bile acid and cholesterol homeostasis. Although the precise mechanism whereby SHP represses transcription is not known, E1A-like inhibitor of differentiation (EID1) was isolated as...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhi, Xiaoyong, Zhou, X. Edward, He, Yuanzheng, Zechner, Christoph, Suino-Powell, Kelly M., Kliewer, Steven A., Melcher, Karsten, Mangelsdorf, David J., Xu, H. Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896210/
https://ncbi.nlm.nih.gov/pubmed/24379397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322827111
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge