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Robotically-Assisted Titration Coupled to Ion Mobility-Mass Spectrometry Reveals the Interface Structures and Analysis Parameters Critical for Multiprotein Topology Mapping

Multiprotein complexes have three-dimensional shapes and dynamic functions that impact almost every aspect of biochemistry. Despite this, our ability to rapidly assess the structures of such macromolecules lags significantly behind high-throughput efforts to identify their function, especially in th...

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Detalhes bibliográficos
Main Authors: Zhong, Yueyang, Feng, Jun, Ruotolo, Brandon T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895495/
https://ncbi.nlm.nih.gov/pubmed/24164205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac402276k
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