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Robotically-Assisted Titration Coupled to Ion Mobility-Mass Spectrometry Reveals the Interface Structures and Analysis Parameters Critical for Multiprotein Topology Mapping
Multiprotein complexes have three-dimensional shapes and dynamic functions that impact almost every aspect of biochemistry. Despite this, our ability to rapidly assess the structures of such macromolecules lags significantly behind high-throughput efforts to identify their function, especially in th...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3895495/ https://ncbi.nlm.nih.gov/pubmed/24164205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac402276k |
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