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Identification of a selective small molecule inhibitor series targeting the Eyes Absent 2 (Eya2) phosphatase activity
Eya proteins are essential co-activators of the Six family of homeobox transcription factors and also contain a unique protein tyrosine phosphatase activity, belonging to the haloacid dehalogenase family of phosphatases. The phosphatase activity of Eya is important for a subset of Six1-mediated tran...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893891/ https://ncbi.nlm.nih.gov/pubmed/22820394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112453936 |
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