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Identification of a selective small molecule inhibitor series targeting the Eyes Absent 2 (Eya2) phosphatase activity

Eya proteins are essential co-activators of the Six family of homeobox transcription factors and also contain a unique protein tyrosine phosphatase activity, belonging to the haloacid dehalogenase family of phosphatases. The phosphatase activity of Eya is important for a subset of Six1-mediated tran...

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Hlavní autoři: Krueger, Aaron B., Dehdashti, Seameen J., Southall, Noel, Marugan, Juan J, Ferrer, Marc, Li, Xueni, Ford, Heide L., Zheng, Wei, Zhao, Rui
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893891/
https://ncbi.nlm.nih.gov/pubmed/22820394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112453936
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