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Critical functions of priming and lysosomal damage for NLRP3 activation
Inflammasomes are cytosolic multi-protein complexes that form in response to infectious or injurious challenges. Inflammasomes control the activity of caspase-1, which is essential for the maturation and release of IL-1b family cytokines. The NLRP1, IPAF and AIM2 inflammasomes recognize specific sub...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893565/ https://ncbi.nlm.nih.gov/pubmed/20201015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200940185 |
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